Spreading shrub up to 1.5-2 m tall, with very hard wood. The branches are thin, twig-like, bare, straight, light yellow (old ones with light gray bark). The leaves are alternate, simple, entire, entire or with an irregularly cut edge, oval, pistillate – solitary (or 3-8), with a spherical ovary and three columns; stamens – arranged in bundles of 3-12, glands are dentate, sepals are concave, stamens are longer than the calyx, ovary is rudimentary. The fruit is a three-celled, rounded three-lobed capsule. The seeds are smooth. Blossoms in June, fruits ripen in September.
Securinega is common in Eastern Siberia (Nerchinsk Dauria) and in the Russian Far East.
Medicinal raw materials are leaves, stems no thicker than 3 mm.
The active principle is the alkaloid sekurenen, the content of which reaches 0.3%. Preparations containing securine have a stimulating effect on the central nervous system, especially increase the excitability of the spinal cord (securine is similar in nature to strychnine, but is 8-10 times less toxic and inferior to it in terms of strength of action).
It is used in the form of securenin nitrate in asthenic conditions, neurasthenia, fatigue, paresis and flaccid paralysis (during the recovery period after poliomyelitis), with sexual weakness due to functional nervous disorders.
Application
0.4% solution of 10-20 drops per reception 2-3 times every day.
Strict dosage!